Associate Director Cancer Genomics


Job Description

The Associate Director Cancer Genomics will support BeiGene’s compound development programs by assessing genomic biomarkers and signatures across retrospective and prospective datasets, with the goal of developing novel companion diagnostics as appropriate. The incumbent will play a key role in positioning BeiGene as a leader in the field of personalized medicine, and is expected to have deep scientific expertise in genomic platforms relevant to biomarker development, and a demonstrated success in mining and developing genomic signatures to support cancer drug development. The individual will report to the Vice President of Translational Research and Biomarkers.

Job Summary

As an integral member of the Translational Research team, this position will be responsible for supporting biomarker discovery and diagnostic development for BeiGene’s pipeline in different cancer indications. Under the guidance of the Vice President, this position will work effectively with Clinical Development, Biostatistics, Regulatory, and Clinical Operations groups to design and implement biomarker plans for BeiGene sponsored and other clinical studies. He/she will analyze and interpret molecular/clinical data, and prepare reports for scientific publications and regulatory submissions. The ability to develop and manage strategic collaborations with key third parties, including academic and commercial vendors, is an essential element of the role.

Job Responsibilities

The key tasks will initially include (at least) the following:

  • Design and execute biomarker plans for ongoing and future sponsored clinical studies
  • Integrate molecular and clinical data to identify predictive biomarkers
  • Support analytical and clinical validation experiments for companion diagnostics assays
  • Compose and review patient identification and biomarker sections of clinical protocols and regulatory documents
  • Evaluate assays from different molecular diagnostic vendors, including vendor selection, study execution, interpretation and report writing
  • Collaborate with leading academic laboratories to optimize biomarkers and study primary and acquired resistance mechanisms
  • Present scientific/clinical findings in key conferences and prepare for publications


  • A PhD in molecular biology, genetics, bioinformatics, or related field, with at least five years of research experience in cancer genetics and/or genomics is required, preferably in the biotechnology/diagnostics industry.
  • Possessing expertise in cancer genomic analysis and an enthusiasm for personalized medicine is required
  • Demonstrated success in the field of oncology with an ability to leverage cutting edge technology platforms is required
  • Experience with developing molecular diagnostic assays is required
  • Experience with analyzing molecular data from clinical trial specimens is required
  • Experience with analyzing mass genomic data (next generation sequencing, SNP and gene expression arrays) from internal and public datasets is required
  • Prior experience with vendor selection and management required
  • Experience with analytical and clinical validation of companion diagnostics is preferred
  • Expertise in the field of DNA damage repair pathway and immuno-oncology is preferred
  • Professional knowledge and hands-on scientific expertise and skills in developing novel biomarker platforms is preferred
  • Knowledge of oncology drug development is preferred
  • Team player with demonstrated success with cross-functional and global teams is preferred
  • Experience with the development and support of related SOPs and ICF’s is preferred
  • Experience with partnerships and strategic alliances is preferred
  • Experience working in global environment is preferred
  • Prior management of budgets and timelines is preferred

Capabilities and Competencies

  • Scientific and technical expert on biomarkers
  • Values based collaborator – respectful, accountable and collaborative
  • Ability to relate and work with a wide range of people to achieve results
  • Impactful written and verbal scientific communication
  • Successful and superior influencing skills across all levels of the organization and external collaborators
  • Problem solving and risk-mitigation skills
  • Strong time management, organizational skills, and ability to prioritize and multi-task
  • Appreciation of diversity and multiculturalism
  • Strategic and creative thinker
  • Ability to build working relations throughout the organization and with business partners to achieve business goals


San Francisco Bay Area, Emeryville or San Mateo

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