Conference Presentations

Gupta SK, Nagel ZD, Carlson BL, Schroeder MA, Bakken KK, Mladek AC, Samson L, Kitange GJ, Sarkaria JN Inhibition of PARP Activity by BGB-290 Potentiates Efficacy of Temozolomide in Patient Derived Xenografts of Glioblastoma Multiforme 2015 American Association for Cancer Research Annual Meeting, Philadelphia, PA

Li N, Sun Z, Liu Y, Guo M, Zhang Y, Zhou D, Zhang B, Su D, Zhang S, Han J, Gao Y, Guo Y, Wang Z, Wei M, Luo L, Wang L BGB-3111 is a Novel and Highly Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor 2015 American Association for Cancer Research Annual Meeting, Philadelphia, PA

Sun Z, Zhou D, Luo L Effect of BTK Inhibitors on Differentiation of Human Monocyte-derived Dendritic Cells 2015 American Association for Cancer Research Annual Meeting, Philadelphia, PA

Tang Z, Jiang B, Shi Z, Gong W, Liu Y, Wang X, Gao Y, Yu F, Liu Y, Zhou C, Luo L, Wei M, Wang L BGB-290: A Novel PARP Inhibitor with Unique Brain Penetration Ability Demonstrated Strong Synergism with Temozolomide in Subcutaneous and Intracranial Xenograft Models 2015 American Association for Cancer Research Annual Meeting, Philadelphia, PA

Tang Z, Liu Y, Qin Z, Ren B, Shi Z, Gong W, Liu Y, Wang X, Gao Y, Yu F, Jiang B, Wei M, Zhou C, Luo L, Li Z, Yu J, Zhao J, Wang J, Wang L BGB-290: A Highly Potent and Specific PARP1/2 Inhibitor Potentiates Anti-tumor Activity of Chemotherapeutics in Patient Biopsy Derived SCLC Models 2015 American Association for Cancer Research Annual Meeting, Philadelphia, PA

Tang Z, Yuan X, Du R, Cheung S, Zhang G, Wei J, Zhao Y, Feng Y, Peng H, Zhang Y, Du Y, Hu X, Gong W, Liu Y, Gao Y, Hao R, Ji J, Zhang L, Li S, Sutton D, Wei M, Zhou C, Wang L, Luo L BGB-283, a Novel RAF Kinase and EGFR dual inhibitor, Displays Potent Antitumor Activity in B-RAF Mutated Colorectal Cancers 2015 American Association for Cancer Research Annual Meeting, Philadelphia, PA

Yuan X, Tang Z, Du R, Cheung SH, Wei J, Zhao Y, Du Y, Hao R, Hu X, Gong W, Liu Y, Gao Y, Wei M, Zhou C, Wang L, Luo L BGB-283 Effectively Enhances MEK Inhibitor Induced Tumor Suppression in RAS Mutant Cancers 2015 American Association for Cancer Research Annual Meeting, Philadelphia, PA

Li N, Sun Z, Liu Y, Guo A, Zhang Y, Zhou D, Zhang B, Su D, Zhang S, Han J, Gao Y, Guo Y, Wang Z, Wei M, Luo L, Wang L BGB-3111 is a Novel and Highly Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor 2014 American Society of Hematology Meeting, San Francisco, CA

Sun Z, Zhou D, Wei M, Wang L, Luo L Mechanism of Action of Ibrutinib in Mantle Cell Lymphoma 2014 American Association for Cancer Research Annual Meeting, San Diego, CA